Article
Differential beta-adrenergic regulation and phenotypic modulation of voltage-gated calcium currents in rat aortic myocytes.
The Journal of physiology - 1 Sept 1994
Neveu D, Quignard J F, Fernandez A, Richard S, Nargeot J
Abstract excerpt
1. We studied the beta-adrenergic regulation of voltage-gated Ca2+ channel currents using the whole-cell patch-clamp technique (18-22 degrees C) in freshly isolated and in cultured (1-20 days) rat aortic vascular smooth muscle cells (VSMCs). These currents include a transient low-voltage-activate...
Topics
- Animals
- Aorta
- Bucladesine
- Calcium Channels
- Cell Cycle
- Cells, Cultured
- DNA
- Ion Channel Gating
- Isoproterenol
- Male
- Membrane Potentials
- Muscle, Smooth, Vascular
- Patch-Clamp Techniques
- Phenotype
- Rats
- Rats, Wistar
- Receptors, Adrenergic, beta