Investigation of the relationship between osteoporosis and the collagenase gene by means of polymorphism of the 5'upstream region of this gene.

doi:10.1007/BF00298750

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Article

Investigation of the relationship between osteoporosis and the collagenase gene by means of polymorphism of the 5'upstream region of this gene.

Calcified tissue international - 1 Jan 1995

Thiry-Blaise L M, Taquet A N, Reginster J Y, Nusgens B, Franchimont P, Lapière C M

Abstract excerpt

Osteoporosis is a slowly progressing disease resulting from an imbalance between bone accretion and degradation. As interstitial collagenase is a key enzyme in the degradation of bone matrix, we investigated a possible relationship between the collagenase gene and osteoporosis. Analysis of an amp...

Topics

Adult
Alleles
Base Sequence
Collagenases
DNA
DNA Primers
Female
Gene Frequency
Humans
Male
Middle Aged
Molecular Sequence Data
Osteoporosis
Osteoporosis, Postmenopausal
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 7796353
DOI: 10.1007/BF00298750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7796353-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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