Article
The importance of polymorphic variants of collagen 1A2 gene (COL1A2) in the development of osteopenia and osteoporosis in postmenopausal women.
Ginekologia polska - 1 Jan 2017
Majchrzycki Marian, Bartkowiak-Wieczorek Joanna, Bogacz Anna, Szyfter-Harris Joanna, Wolski Hubert, Klejewski Andrzej, Goch Maciej, Drews Krzysztof, Barlik Magdalena, Ożarowski Marcin, Kamiński Adam, Gryszczyńska Agnieszka, Seremak-Mrozikiewicz Agnieszka
Abstract excerpt
OBJECTIVES: Collagen type I plays an important role in the bone matrix and is encoded by COL1A2 (collagen type I alpha 2) gene that may be a potential candidate for osteoporotic fracture. The aim of this study is to determine whether EcoRI, Del38 and PvuII polymorphisms of COL1A2 are associated with the development of osteoporosis and osteopenia in post-menopausal Polish women. Moreover, analysis of relationship...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.