Article
Mitochondrial mutations and human disease.
Environmental and molecular mutagenesis - 1 Jan 1995
Grossman L I
Abstract excerpt
The mitochondrial genome is essential for producing ATP (adenosine 5'-triphosphate) via oxidative phosphorylation. The gradual decline of mitochondrial function with age has long been postulated as a factor in aging. More recently, a variety of diseases have been related to molecular defects in human mitochondrial DNA. In both the cases of aging and disease, symptoms were generally neuromuscular, reflecting the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.