Article
Mitochondrial genetics and human disease.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Dec 1996
Grossman L I, Shoubridge E A
Abstract excerpt
Mitochondria contain a molecular genetic system to express the 13 protein components of the electron transport system encoded in the mitochondrial genome (mtDNA). Defects in the function of this system result in some diseases, many of which are multisystem disorders, prominently involving highly...
Topics
- Aged
- Base Sequence
- DNA, Mitochondrial
- Gene Rearrangement
- Genotype
- Humans
- Mitochondria
- Mitochondrial Myopathies
- Molecular Sequence Data
- Mutation
- Oxygen Consumption
- Phenotype