Article
Mosaicism: the embryo as a target for induction of mutations leading to cancer and genetic disease.
Environmental and molecular mutagenesis - 1 Jan 1995
Mohrenweiser H, Zingg B
Abstract excerpt
Mosaicism, the existence of "patches" of cells with a genetic constitution that differs from that of other cells of an organism, has been observed in both germinal and somatic tissues of several species, including humans. Mutational events occurring during early embryogenesis can give rise to an...
Topics
- Animals
- Embryonic and Fetal Development
- Genetic Diseases, Inborn
- Humans
- Mosaicism
- Mutation
- Neoplasms
- Risk Factors