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Article

Transplacental transfer of environmental genotoxins: polycyclic aromatic hydrocarbon-albumin in non-smoking women, and the effect of maternal GSTM1 genotype.

Carcinogenesis - 1 Jun 1995

Autrup H, Vestergaard A B, Okkels H

Abstract excerpt

Transplacental transfer of genotoxic material has been determined by measuring the polycyclic aromatic hydrocarbon-albumin adduct level in serum isolated from the mother and the umbilical cord using a competitive ELISA assay and the antibody (8E11) against benzo[a]pyrene (B[a]P) tetrols. Smoking women (median 5.54 fmol B[a]P equiv/microgram albumin; 21 cases) and non-smoking women living in rural areas (median...

Topics

Adult
Environmental Exposure
Environmental Pollutants
Female
Fetal Blood
Genotype
Glutathione Transferase
Humans
Maternal-Fetal Exchange
Polycyclic Compounds
Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Serum Albumin

Smoking

Tobacco Smoke Pollution

Source

Identifiers

PMID: 7788847
DOI: 10.1093/carcin/16.6.1305

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7788847-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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