Article
Glucose repression can be alleviated by reducing glucose phosphorylation rate in Saccharomyces cerevisiae.
Scientific reports - 8 Feb 2018
Lane Stephan, Xu Haiqing, Oh Eun Joong, Kim Heejin, Lesmana Anastashia, Jeong Deokyeol, Zhang Guochang, Tsai Ching-Sung, Jin Yong-Su, Kim Soo Rin
Abstract excerpt
Microorganisms commonly exhibit preferential glucose consumption and diauxic growth when cultured in mixtures of glucose and other sugars. Although various genetic perturbations have alleviated the effects of glucose repression on consumption of specific sugars, a broadly applicable mechanism remains unknown. Here, we report that a reduction in the rate of glucose phosphorylation alleviates the effects of glucose...
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