Article
Defining a novel cis element in the 3'-untranslated region of mammalian ribonucleotide reductase component R2 mRNA: role in transforming growth factor-beta 1 induced mRNA stabilization.
Nucleic acids research - 11 May 1995
Amara F M, Chen F Y, Wright J A
Abstract excerpt
Ribonucleotide reductase R2 gene expression is elevated in BALB/c 3T3 fibroblasts treated with transforming growth factor beta 1. We investigated the possibility that the 3'-UTR of ribonucleotide reductase R2 mRNA contains regulatory information for TGF-beta 1 induced message stability. Using end...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- Binding Sites
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
- Protein Binding
- RNA, Messenger
- Ribonucleotide Reductases
- Sequence Analysis
- Transforming Growth Factor beta