Article
Mutants of dermatophytes resistant to ketoconazole.
Acta Universitatis Palackianae Olomucensis Facultatis Medicae - 1 Jan 1994
Lenhart K, Merkunová A
Abstract excerpt
Authors describe the frequency and properties of mutants resistant to ketoconazole, obtained from the dermatophytes Microsporum gypseum and Trichophyton mentagrophytes. Spontaneous mutants occurred with the frequency of 10(-9) to spore and nucleus. Ultraviolet radiation increased the frequency of mutants by two numeric orders. The resistance level was relatively small in both types of mutants (RL within the range...
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