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Article

Effect of ketoconazole on potassium pool, c-AMP-release and ergosterol synthesis in resistant mutants of Microsporum gypseum.

Acta Universitatis Palackianae Olomucensis Facultatis Medicae - 1 Jan 1994

Merkunová A, Lenhart K

Abstract excerpt

The effect of ketoconazole (KK) on chosen biochemical indexes was studied in three mutants of dermatophyte Microsporum gypseum (MG-155 wild strain) resistant to KK. Fungistatic concentration of KK added to liquid cultivate medium increases significantly ergosterol pool and nonsignificantly demeth...

Topics

Cyclic AMP
Drug Resistance, Microbial
Ergosterol
Ketoconazole
Microsporum
Mutation
Potassium

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7778499

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7778499-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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