Article
Expression of differentiation-related phenotypes and apoptosis are independently regulated during myeloid cell differentiation.
Journal of biochemistry - 1 Jan 1995
Terui Y, Furukawa Y, Sakoe K, Ohta M, Saito M
Abstract excerpt
When human promyelocytic leukemia cell line HL-60 was treated with various differentiation-inducers, apoptosis always occurred after the full appearance of differentiation-related phenotypes. However, the two phenomena could be dissociated when HL-60 cells were treated with PDBu. When HL-60 cells were cultured with PDBu for more than 36 h, apoptosis was induced following differentiation. Apoptosis was not,...
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