Pre-eclampsia is associated with an excess of proliferative immature intermediate trophoblast.

doi:10.1016/0046-8177(95)90162-0

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Article

Pre-eclampsia is associated with an excess of proliferative immature intermediate trophoblast.

Human pathology - 1 Jun 1995

Redline R W, Patterson P

Abstract excerpt

Pre-eclampsia/toxemia (PET) is an idiopathic hypertensive disorder of pregnancy elicited in susceptible mothers by exposure to placental trophoblast. Three facts regarding the placenta in PET are known: an association with large placentas (excessive trophoblast), a tendency for superficial implantation, and inappropriate trophoblastic immaturity, as assessed by ultrastructural and biochemical criteria. A unitary...

Topics

Biomarkers
Cell Division
Female
Gestational Age
Humans
Phenotype
Placenta
Placental Lactogen
Pre-Eclampsia
Pregnancy
Proliferating Cell Nuclear Antigen
Proto-Oncogene Proteins

Proto-Oncogene Proteins c-bcl-2

Trophoblasts

beta 2-Microglobulin

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