Article
Protein tyrosine phosphatase-induced hyperactivity is a conserved strategy of a subset of baculoviruses to manipulate lepidopteran host behavior.
PloS one - 1 Jan 2012
van Houte Stineke, Ros Vera I D, Mastenbroek Tom G, Vendrig Nadia J, Hoover Kelli, Spitzen Jeroen, van Oers Monique M
Abstract excerpt
Many parasites manipulate host behavior to increase the probability of transmission. To date, direct evidence for parasitic genes underlying such behavioral manipulations is scarce. Here we show that the baculovirus Autographa californica nuclear polyhedrovirus (AcMNPV) induces hyperactive behavior in Spodoptera exigua larvae at three days after infection. Furthermore, we identify the viral protein tyrosine...
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