Article
Comparative proteomics reveal fundamental structural and functional differences between the two progeny phenotypes of a baculovirus.
Journal of virology - 1 Jan 2013
Hou Dianhai, Zhang Leike, Deng Fei, Fang Wei, Wang Ranran, Liu Xijia, Guo Lin, Rayner Simon, Chen Xinwen, Wang Hualin, Hu Zhihong
Abstract excerpt
The replication of lepidopteran baculoviruses is characterized by the production of two progeny phenotypes: the occlusion-derived virus (ODV), which establishes infection in midgut cells, and the budded virus (BV), which disseminates infection to different tissues within a susceptible host. To understand the structural, and hence functional, differences between BV and ODV, we employed multiple proteomic methods...
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