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Article

Identification and analysis of aarP, a transcriptional activator of the 2'-N-acetyltransferase in Providencia stuartii.

Journal of bacteriology - 1 Jun 1995

Macinga D R, Parojcic M M, Rather P N

Abstract excerpt

The aarP gene has been identified in a search for activators of the 2-N-acetyltransferase [encoded by aac(2')-Ia] in Providencia stuartii. Introduction of aarP into P. stuartii on a multicopy plasmid resulted in a 9.9-fold increase in the accumulation of beta-galactosidase from an aac(2')-lacZ fu...

Topics

Acetyltransferases
Amino Acid Sequence
Bacterial Proteins
Base Sequence
Gene Expression Regulation, Bacterial
Molecular Sequence Data
Mutagenesis
Phenotype
Providencia
Sequence Homology, Amino Acid
Trans-Activators

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Identifiers

PMID: 7768849
DOI: 10.1128/jb.177.12.3407-3413.1995
PMCID: PMC177042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7768849-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Identification and analysis of aarP, a transcriptional activator of the 2'-N-acetyltransferase in Providencia stuartii.PMID 7768849Read ↗

Identification and characterization of aarF, a locus required for production of ubiquinone in Providencia stuartii and Escherichia coli and for expression of 2'-N-acetyltransferase in P. stuartii.Semantic proximity Read ↗

aarC, an essential gene involved in density-dependent regulation of the 2'-N-acetyltransferase in Providencia stuartii.Semantic proximity Read ↗

Role of SspA in the density-dependent expression of the transcriptional activator AarP in Providencia stuartii.Semantic proximity Read ↗

aarD, a Providencia stuartii homologue of cydD: role in 2'-N-acetyltransferase expression, cell morphology and growth in the presence of an extracellular factor.Semantic proximity Read ↗

A regulatory cascade involving AarG, a putative sensor kinase, controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii.Semantic proximity Read ↗

Mutations in aarE, the ubiA homolog of Providencia stuartii, result in high-level aminoglycoside resistance and reduced expression of the chromosomal aminoglycoside 2'-N-acetyltransferase.Semantic proximity Read ↗

Rhomboid protease AarA mediates quorum-sensing in Providencia stuartii by activating TatA of the twin-arginine translocase.Semantic proximity Read ↗

Functional characterization of Escherichia coli GlpG and additional rhomboid proteins using an aarA mutant of Providencia stuartii.Semantic proximity Read ↗

Contribution of gentamicin 2'-N-acetyltransferase to the O acetylation of peptidoglycan in Providencia stuartii.Semantic proximity Read ↗

Role of CysE in production of an extracellular signaling molecule in Providencia stuartii and Escherichia coli: loss of CysE enhances biofilm formation in Escherichia coli.Semantic proximity Read ↗

Cloning and DNA sequence of amiC, a new gene regulating expression of the Pseudomonas aeruginosa aliphatic amidase, and purification of the amiC product.Semantic proximity Read ↗

The role of O-acetylation in the metabolism of peptidoglycan in Providencia stuartii.Semantic proximity Read ↗

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