Article
Rhomboid protease AarA mediates quorum-sensing in Providencia stuartii by activating TatA of the twin-arginine translocase.
Proceedings of the National Academy of Sciences of the United States of America - 16 Jan 2007
Stevenson Lindsay G, Strisovsky Kvido, Clemmer Katy M, Bhatt Shantanu, Freeman Matthew, Rather Philip N
Abstract excerpt
The Providencia stuartii AarA protein is a member of the rhomboid family of intramembrane serine proteases and is required for the production of an unknown quorum-sensing molecule. In a screen to identify rhomboid-encoding genes from Proteus mirabilis, tatA was identified as a multicopy suppressor and restored extracellular signal production as well as complementing all other phenotypes of a Prov. stuartii aarA...
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