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Article

Mitomycin C stimulates thermally induced recombinant gene expression in Escherichia coli MC strains.

Applied microbiology and biotechnology - 1 Mar 1995

Corchero J L, Carbonell X, Benito A, Villaverde A

Abstract excerpt

The effects of mitomycin C on C1857-controlled recombinant gene expression have been explored in E. coli cultures when the drug was added simultaneously to the thermal induction. A significantly improved yield of homologous, heterologous and chimeric fusion proteins was observed in E. coli MC1061 and GE864 (a MC4100 derivative) thermoinduced cells. This feature was not detected in other E. coli strains and does...

Topics

DNA, Bacterial
Escherichia coli
Gene Expression Regulation, Bacterial
Mitomycin
Phenotype
Plasmids
Rec A Recombinases
Recombinant Fusion Proteins
Recombination, Genetic
SOS Response, Genetics
Temperature

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beta-Galactosidase

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Identifiers

PMID: 7766090
DOI: 10.1007/BF00191187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7766090-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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