The rapid degradation of mutant SecA protein in the Bacillus subtilis secA341 (ts) mutant causes a protein translocation defect in the cell.

doi:10.1271/bbb.58.1845

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Article

The rapid degradation of mutant SecA protein in the Bacillus subtilis secA341 (ts) mutant causes a protein translocation defect in the cell.

Bioscience, biotechnology, and biochemistry - 1 Oct 1994

Takamatsu H, Nakane A, Sadaie Y, Nakamura K, Yamane K

Abstract excerpt

To study the function of SecA protein and the protein translocation system of Bacillus subtilis, wild-type and mutant SecA proteins were characterized in vivo and in vitro. SecA protein was abundant in a wild-type strain (168) and existed in a stable homodimer. In contrast to this, SecA341 (ts) protein having an amino acid replacement from proline to leucine at residue 431 was undetectable by immunoblotting in...

Topics

Adenosine Triphosphatases
Bacillus subtilis
Bacterial Proteins
Biological Transport
Chromatography, Gel
Endopeptidases
Escherichia coli Proteins
Hydrolysis
Immunoblotting
Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Plasmids

SEC Translocation Channels

SecA Proteins

Translocation, Genetic

Trypsin

beta-Lactamases

Source

Open in PubMed

Identifiers

PMID: 7765510
DOI: 10.1271/bbb.58.1845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7765510-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The rapid degradation of mutant SecA protein in the Bacillus subtilis secA341 (ts) mutant causes a protein translocation defect in the cell.PMID 7765510Read ↗

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