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Article

Single base polymorphism linked to the ataxia-telangiectasia locus is detected by mismatch PCR.

Biochemical and biophysical research communications - 25 May 1995

Athma P, Fidahusein N, Swift M

Abstract excerpt

A polymorphic site at D11S384, which shows zero recombination with the ataxia-telangiectasia (A-T) locus, was originally detected by Mutation Detection Enhancement Gel and Denaturing Gradient Gel Electrophoresis. In order to increase the throughput and decrease the complexity of the assays, we developed a site directed mutagenesis using primers with mismatched 3' ends, followed by restriction digestion, as a...

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Identifiers

PMID: 7763272
DOI: 10.1006/bbrc.1995.1753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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