Article
An efficient method to isolate yeast genes causing overexpression-mediated growth arrest.
Yeast (Chichester, England) - 1 Jan 1995
Espinet C, de la Torre M A, Aldea M, Herrero E
Abstract excerpt
In order to characterize new yeast genes regulating cell proliferation, a number of overexpression-sensitive clones have been isolated from a Saccharomyces cerevisiae cDNA library in a multicopy vector under the control of the GAL1 promoter, on the basis of growth arrest phenotype under galactose-induction conditions. Thirteen of the independent clones isolated in this way correspond to previously known genes...
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