Impaired spermatogenesis in the twitcher mouse: A morphological evaluation from the seminiferous tubules to epididymal transit.

doi:10.1080/19396368.2016.1271918

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Article

Impaired spermatogenesis in the twitcher mouse: A morphological evaluation from the seminiferous tubules to epididymal transit.

Systems biology in reproductive medicine - 1 Apr 2017

Luddi Alice, Gori Martina, Crifasi Laura, Marrocco Camilla, Belmonte Giuseppe, Costantino-Ceccarini Elvira, Piomboni Paola

Abstract excerpt

Spermatogenesis is a complex process of proliferation and differentiation during male germ cell development whereby undifferentiated spermatogonial germ cells evolve into maturing spermatozoa. In this developmental process the interactions between different cell types are finely regulated, hence any disruption in these relationships leads to male infertility. The twitcher mouse, the murine model of Krabbe...

Topics

Animals
Disease Models, Animal
Epididymis
Galactosylceramidase
Genetic Predisposition to Disease
Infertility, Male
Leukodystrophy, Globoid Cell
Male
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Electron, Scanning

Microscopy, Electron, Transmission

Phenotype

Seminiferous Tubules

Spermatogenesis

Spermatozoa

Source

Open in PubMed

Identifiers

PMID: 28103109
DOI: 10.1080/19396368.2016.1271918

Genes

GALC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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