Article
Restoration of hepatic mast cells and expression of a different mast cell protease phenotype in regenerating rat liver after 70%-hepatectomy.
Immunology and cell biology - 1 Dec 2005
Zweifel Martin, Breu Karin, Matozan Katja, Renner Eberhard, Welle Monika, Schaffner Thomas, Clavien Pierre-Alain
Abstract excerpt
Mast cells (MC) can undergo significant changes in number and phenotype; these alterations result in the differential expression of growth factors and cytokines. Kit ligand (KL; stem cell factor) is produced by mesenchymal cells, and in the liver by biliary epithelial cells. Recent studies suggest that KL, and its receptor c-kit, may be involved in liver regeneration after loss of liver mass. However, KL is also...
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