Article
Lack of association between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and idiopathic dilated cardiomyopathy.
Journal of the American College of Cardiology - 1 Jun 1995
Montgomery H E, Keeling P J, Goldman J H, Humphries S E, Talmud P J, McKenna W J
Abstract excerpt
OBJECTIVES: We sought to investigate the role of polymorphisms of the gene for angiotensin-converting enzyme in the development and progression of idiopathic dilated cardiomyopathy. BACKGROUND: Cardiovascular renin-angiotensin systems may be involved in cardiac remodeling and fibrosis. The absence (deletion [D]) of a 287-base pair marker in the angiotensin-converting enzyme gene (introm 16) is associated with...
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