Article
Extensive polymorphism of a (CA)n microsatellite located in the HLA-DQA1/DQB1 class II region.
Human immunology - 1 Mar 1995
Macaubas C, Hallmayer J, Kalil J, Kimura A, Yasunaga S, Grumet F C, Mignot E
Abstract excerpt
A highly polymorphic (CA)n microsatellite marker (DQCAR), located between the DQA1 and the DQB1 genes, was characterized in four ethnic groups. Based on length polymorphism, 12 alleles could be defined. The marker is located 1- to 2-kb telomeric to the DQB1 gene and 10 kb centromeric to the DQA1 gene and was shown to be in tight linkage disequilibrium with HLA-DQ. Analysis of the linkage disequilibrium pattern...
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