DQCAR microsatellite polymorphism and susceptibility to rheumatoid arthritis.

doi:10.1111/j.1399-0039.1998.tb03003.x

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Article

DQCAR microsatellite polymorphism and susceptibility to rheumatoid arthritis.

Tissue antigens - 1 Jun 1998

Singal D P, Li J, Ye M

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease associated with HLA-DR genes that share a five amino acid sequence motif, QKRAA or QRRAA, from position 70 to 74 in the third hypervariable region of the DRbeta1 molecule. Since the associations between DRB1 genes and susceptibilit...

Topics

Adult
Alleles
Arthritis, Rheumatoid
Genetic Predisposition to Disease
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Microsatellite Repeats
Polymorphism, Genetic

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