Article
Analysis of the CD3 gene region and type 1 diabetes: application of fluorescence-based technology to linkage disequilibrium mapping.
Human molecular genetics - 1 Feb 1995
Pritchard L E, Kawaguchi Y, Reed P W, Copeman J B, Davies J L, Barnett A H, Bain S C, Todd J A
Abstract excerpt
The CD3 gene region on chromosome 11q23 has been implicated in susceptibility to type 1 (insulin-dependent) diabetes mellitus. Using semi-automated fluorescence-based technology, we have undertaken association and linkage analysis of a dinucleotide microsatellite in the CD3 delta (CD3D) gene. We have also performed a large case-control analysis of a restriction fragment length polymorphism (RFLP) in the CD3...
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