Analysis of the CD3 gene region and type 1 diabetes: application of fluorescence-based technology to linkage disequilibrium mapping.

doi:10.1093/hmg/4.2.197

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Article

Analysis of the CD3 gene region and type 1 diabetes: application of fluorescence-based technology to linkage disequilibrium mapping.

Human molecular genetics - 1 Feb 1995

Pritchard L E, Kawaguchi Y, Reed P W, Copeman J B, Davies J L, Barnett A H, Bain S C, Todd J A

Abstract excerpt

The CD3 gene region on chromosome 11q23 has been implicated in susceptibility to type 1 (insulin-dependent) diabetes mellitus. Using semi-automated fluorescence-based technology, we have undertaken association and linkage analysis of a dinucleotide microsatellite in the CD3 delta (CD3D) gene. We have also performed a large case-control analysis of a restriction fragment length polymorphism (RFLP) in the CD3...

Topics

Adolescent
Adult
Alleles
Biomarkers
CD3 Complex
Chromosome Mapping
Diabetes Mellitus, Type 1
Evaluation Studies as Topic
Family Health
Female
Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Haplotypes

Humans

Linkage Disequilibrium

Male

Methods

Pedigree

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 7757067
DOI: 10.1093/hmg/4.2.197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7757067-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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