Article
PCR bias in amplification of androgen receptor alleles, a trinucleotide repeat marker used in clonality studies.
Nucleic acids research - 25 Apr 1995
Mutter G L, Boynton K A
Abstract excerpt
Trinucleotide CAG repeats in the X-linked human androgen receptor gene (HUMARA) have proved a useful means of determining X chromosome haplotypes, and when combined with methylation analysis of nearby cytosine residues permits identification of non-random X inactivation in tumors of women. Co-amplification of two alleles in a heterozygote generates PCR products which differ in the number of CAG units, and thus...
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