Patterns of X chromosome inactivation in sporadic basal cell carcinomas: evidence for clonality.

doi:10.1016/s0190-9622(98)70538-9

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Article

Patterns of X chromosome inactivation in sporadic basal cell carcinomas: evidence for clonality.

Journal of the American Academy of Dermatology - 1 Jan 1998

Walsh D S, Peacocke M, Harrington A, James W D, Tsou H C

Abstract excerpt

BACKGROUND: Some basal cell carcinomas (BCCs) contain genetic mutations, suggesting that the lesion is composed of a monoclonal population of cells. Clonality, a distinguishing feature of neoplasia, can be inferred by referencing clonal markers such as the pattern of X chromosome inactivation. Th...

Topics

Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
Carcinoma, Basal Cell
Cell Lineage
Clone Cells
DNA, Neoplasm
Epithelial Cells
Female
Gene Expression Regulation, Neoplastic
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Polymorphism, Genetic

Receptors, Androgen

Reproducibility of Results

Skin

Source

Open in PubMed

Identifiers

PMID: 9448205
DOI: 10.1016/s0190-9622(98)70538-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9448205-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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