Effects of immunological responsiveness on Langerhans cell behavior in contact sensitization.

doi:10.1111/j.1600-0625.1994.tb00288.x

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Article

Effects of immunological responsiveness on Langerhans cell behavior in contact sensitization.

Experimental dermatology - 1 Dec 1994

Kolde G

Abstract excerpt

The epicutaneous application of haptens results in a functional activation of the antigen-presenting Langerhans cells (LCs) which is necessary for the induction of contact sensitivity. In this ultrastructural study, we investigated the effects of the immune response on these cellular properties of the LCs by using 2 strains of guinea pigs with genetically determined high and non responsiveness, respectively, to...

Topics

Administration, Cutaneous
Animals
Cell Adhesion
Cyclopropanes
Dermatitis, Allergic Contact
Dinitrochlorobenzene
Dinitrofluorobenzene
Disease Susceptibility
Endocytosis
Epidermis
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Guinea Pigs

Immune Tolerance

Injections, Intravenous

Langerhans Cells

Lymphocyte Culture Test, Mixed

Microscopy, Electron

Source

Open in PubMed

Identifiers

PMID: 7749571
DOI: 10.1111/j.1600-0625.1994.tb00288.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7749571-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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