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Article

Protein aggregation kinetics in an Escherichia coli strain overexpressing a Salmonella typhimurium CheY mutant gene.

Applied and environmental microbiology - 1 Apr 1995

Klein J, Dhurjati P

Abstract excerpt

The tendency of recombinant protein in bacteria to partition into soluble and insoluble forms is attributed, in general, to a kinetic competition between protein folding and aggregation. However, little experimental work has actually been performed in vivo on the kinetics and mechanisms of protein folding and aggregation. Results are presented here from radiolabeling experiments which monitored the kinetics of...

Topics

Bacterial Proteins
Chloramphenicol
Escherichia coli
Escherichia coli Proteins
Genes, Bacterial
Inclusion Bodies
Kinetics
Membrane Proteins
Methyl-Accepting Chemotaxis Proteins
Mutation
Protein Conformation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Folding

Recombinant Proteins

Salmonella typhimurium

Solubility

Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 7747944
DOI: 10.1128/aem.61.4.1220-1225.1995
PMCID: PMC167376

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7747944-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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