Article
Maternally inherited diabetes mellitus: the role of mitochondrial DNA defects.
Diabetic medicine : a journal of the British Diabetic Association - 1 Feb 1995
Alcolado J C, Thomas A W
Abstract excerpt
Several studies have shown a consistent maternal effect in the transmission of Type 2 diabetes (NIDDM). The mitochondrial encephalomyopathies are a group of diseases characterized by maternal inheritance and a variety of mitochondrial DNA defects. Diabetes is a feature of some of these disorders and therefore the hypothesis arose that mitochondrial DNA mutations might play a role in patients with diabetes but no...
Topics
- DNA, Mitochondrial
- Deafness
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Family
- Female
- Humans
- Male
- Mothers
- Mutation
- Polymorphism, Genetic
- Sex Characteristics
