Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial DNA variations in patients with maternally inherited diabetes and deafness syndrome.

Biochemical and biophysical research communications - 2 Nov 2000

Perucca-Lostanlen D, Narbonne H, Hernandez J B, Staccini P, Saunieres A, Paquis-Flucklinger V, Vialettes B, Desnuelle C

Abstract excerpt

Mitochondrial DNA (mtDNA) variants have been implicated in the pathogenesis of diabetes. A mutation in the tRNA leucine gene at position 3243 has been previously reported in mtDNA of maternally inherited diabetes and deafness (MIDD) patients. Because the true prevalence of the mitochondrial origin in diabetes may be underestimated, we searched for potentially diabetogenic anomalies of mtDNA in 9 patients highly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Deafness

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus

Share to DNA, Mitochondrial

Share to Genetic Variation

Share to Syndrome

Source

Identifiers

PMID: 11062027
DOI: 10.1006/bbrc.2000.3751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial DNA variations in patients with maternally inherited diabetes and deafness syndrome.PMID 11062027Read ↗

Role of mitochondrial DNA in diabetes Mellitus Type I and Type IISemantic proximity Read ↗

The Mutations and Clinical Variability in Maternally Inherited Diabetes and Deafness: An Analysis of 161 Patients.Semantic proximity Read ↗

Molecular and clinical aspects of mitochondrial diabetes mellitus.Semantic proximity Read ↗

Analysis of association among clinical features and shorter leukocyte telomere length in mitochondrial diabetes with m.3243A>G mitochondrial DNA mutation.Semantic proximity Read ↗

The Role of Mitochondrial Mutations and Chronic Inflammation in Diabetes.Semantic proximity Read ↗

MtDNA mutations in maternally inherited diabetes: presence of the 3397 ND1 mutation previously associated with Alzheimer's and Parkinson's disease.Semantic proximity Read ↗

Defining the importance of mitochondrial gene defects in maternally inherited diabetes by sequencing the entire mitochondrial genome.Semantic proximity Read ↗

Clinical phenotype of mitochondrial diabetes due to rare mitochondrial DNA mutations.Semantic proximity Read ↗

Maternally inherited diabetes and deafness (MIDD): a distinct subtype of diabetes associated with a mitochondrial tRNA(Leu)(UUR) gene point mutation.Semantic proximity Read ↗

A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA.Semantic proximity Read ↗

Heterogeneity of diabetes phenotype in patients with 3243 bp mutation of mitochondrial DNA (Maternally Inherited Diabetes and Deafness or MIDD).Semantic proximity Read ↗

Mitochondrial DNA mutations in diabetic heart.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.