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Article

Mammalian genotoxicity assessment of methylene blue in plasma: implications for virus inactivation.

Transfusion - 1 May 1995

Wagner S J, Cifone M A, Murli H, Dodd R Y, Myhr B

Abstract excerpt

BACKGROUND: The risk of adverse consequences of virus-inactivation procedures for plasma and cellular blood components must be less than the risk of transfusion-associated viral disease. Previous studies demonstrated that methylene blue, which is currently used in Europe for virus inactivation in fresh-frozen plasma, can elicit mutations in bacterial test systems. This study investigates the potential for...

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PMID: 7740612
DOI: 10.1046/j.1537-2995.1995.35595259151.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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