Mammalian genotoxicity assessment of methylene blue in plasma: implications for virus inactivation.

doi:10.1046/j.1537-2995.1995.35595259151.x

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Article

Mammalian genotoxicity assessment of methylene blue in plasma: implications for virus inactivation.

Transfusion - 1 May 1995

Wagner S J, Cifone M A, Murli H, Dodd R Y, Myhr B

Abstract excerpt

BACKGROUND: The risk of adverse consequences of virus-inactivation procedures for plasma and cellular blood components must be less than the risk of transfusion-associated viral disease. Previous studies demonstrated that methylene blue, which is currently used in Europe for virus inactivation in...

Topics

Animals
Cell Death
Lymphoma
Methylene Blue
Mice
Mutagens
Mutation
Thymidine Kinase

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