Article
Impact of polymorphisms in the alpha- and beta-fibrinogen gene on plasma fibrinogen concentrations of coronary heart disease patients.
Thrombosis research - 1 Feb 1995
Heinrich J, Funke H, Rust S, Schulte H, Schönfeld R, Köhler E, Assmann G
Abstract excerpt
Despite many investigations in a variety of experimental settings, uncertainty remains concerning the size of the genetic contribution to plasma fibrinogen levels. We used the polymerase chain reaction to amplify the polymorphic sites for the restriction enzymes TaqI in the alpha-fibrinogen gene...
Topics
- Alleles
- Base Sequence
- Coronary Disease
- Fibrinogen
- Gene Frequency
- Genes
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length