Compartmental Localization of Complement Component Transcripts in the Normal Human Kidney

Abstract excerpt

Local synthesis of complement components may play a crucial role in the pathogenesis of renal disease. Previous reports have shown that a number of complement components are produced by renal tissue both in vitro and in disease states. In the present study, we focused on the topographical distribution of components of the alternative and classical activation pathways in normal human kidney. As a whole, the normal...

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