Article
Application of a polymorphic Y microsatellite to the detection of post bone marrow transplantation chimaerism.
British journal of haematology - 1 Mar 1995
Lo Y M, Noakes L, Roux E, Jeannet M, Chapuis B, Fleming K A, Wainscoat J S
Abstract excerpt
A highly sensitive Y-microsatellite amplification system was developed for the detection of post bone marrow transplantation (BMT) chimaerism. The system is able to detect the DNA equivalent of a single male cell in a background of 10(5) female cells. For clinical applications it has the distinct advantage that the polymorphic nature of the PCR product allows the checking of the genuineness of a positive PCR...
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