Article
Are rapidly mutating Y-short tandem repeats useful to resolve a lineage? Expanding mutability data on distant male relationships.
Transfusion - 1 Feb 2016
Turrina Stefania, Caratti Stefano, Ferrian Melissa, De Leo Domenico
Abstract excerpt
BACKGROUND: Y-chromosomal short tandem repeats (Y-STRs) are essential to relate male lineages in forensic and evolutionary studies. Although large panels of Y-STR markers are now available, none possess sufficient discrimination power to distinguish close male relatives. This limit may be overcome by the use of rapidly mutating Y-STRs (RM Y-STRs), characterized by mutation rates higher than common Y-STRs....
Topics
- Adult
- Aged
- Aged, 80 and over
- Chromosomes, Human, Y
- Genetic Loci
- Humans
- Male
- Microsatellite Repeats
- Middle Aged
- Mutation