Individual differences in sensitivity to nicotine: implications for genetic research on nicotine dependence.

doi:10.1007/BF02196925

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Article

Individual differences in sensitivity to nicotine: implications for genetic research on nicotine dependence.

Behavior genetics - 1 Mar 1995

Pomerleau O F

Abstract excerpt

Recent evidence suggests that cigarette smoking has a heritability index around 53%. While related research on underlying mechanisms also supports the idea that genetic factors contribute to nicotine dependence--as well as to cofactors such as substance use and mood disorders--the nature of the b...

Topics

Adaptation, Physiological
Animals
Disease Susceptibility
Dose-Response Relationship, Drug
Drug Tolerance
Female
Genetic Variation
Humans
Male
Models, Psychological
Nicotine
Reinforcement, Psychology
Smoking
Substance-Related Disorders
Tobacco Use Disorder

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