Article
Constitutional mechanisms of vulnerability and resilience to nicotine dependence.
Molecular psychiatry - 1 Jul 2009
Hiroi N, Scott D
Abstract excerpt
The core nature of nicotine dependence is evident in wide variations in how individuals become and remain smokers. Individuals with pre-existing behavioral traits are more likely to develop nicotine dependence and experience difficulty when attempting to quit. Many molecular factors likely contribute to individual variations in the development of nicotine dependence and behavioral traits in complex manners....
Topics
- Animals
- Genetic Predisposition to Disease
- Humans
- Models, Biological
- Monoamine Oxidase
- Nicotine
- Phenotype
- Smoking
- Tobacco Use Disorder