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Article

The genetic determinants of smoking.

Chest - 1 May 2003

Batra Vikas, Patkar Ashwin A, Berrettini Wade H, Weinstein Stephen P, Leone Frank T

Abstract excerpt

Dependence on tobacco, like many other drug dependencies, is a complex behavior with both genetic and environmental factors contributing to the variance. The heritability estimates for smoking in twin studies have ranged from 46 to 84%, indicating a substantial genetic component to smoking. Candidate gene studies have detected functional polymorphisms in genes coding for the cytochrome P450 enzymes, and...

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Identifiers

PMID: 12740294
DOI: 10.1378/chest.123.5.1730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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