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Article

Genetic susceptibility to substance dependence.

Molecular psychiatry - 1 Apr 2005

Hiroi N, Agatsuma S

Abstract excerpt

Despite what is often believed, the majority of those who experiment with substances with a dependence potential do not develop dependence. However, there is a subpopulation of users that easily becomes dependent on substances, and these individuals exhibit pre-existing comorbid traits, including novelty seeking and antisocial behavior. There appears to be a genetic basis for the susceptibility to dependence and...

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PMID: 15583701
DOI: 10.1038/sj.mp.4001622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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