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Article

Molecular cloning of a serine proteinase inhibitor from Brugia malayi

1 May 1995

Abstract excerpt

The antigens produced by the infective-stage larvae of filarial parasites are potentially important targets for a protective immune response. A major impediment to studies on the biochemistry and molecular biology of antigens from infective larvae is a lack of parasite material. By employing a reverse transcription PCR-based strategy which exploited the presence of a conserved 22-nucleotide spliced leader...

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PMID: 7729881
DOI: 10.1128/iai.63.5.1745-1753.1995

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