Article
Duplication of l(2)gd imaginal discs in Drosophila is mediated by ectopic expression of wg and dpp.
Developmental biology - 1 Apr 1995
Buratovich M A, Bryant P J
Abstract excerpt
We investigated the expression of segment polarity genes during the development of overgrowing and duplicating imaginal discs in the lethal overgrowth mutant lethal (2) giant discs (l (2) gd) of Drosophila in order to explore the molecular basis of hyperplasia and axis establishment in imaginal discs. The expression of wingless (wg), detected using an enhancer trap, is initially restricted to a ventral sector of...
Topics
- Animals
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Insect Hormones
- Morphogenesis
- Mutation
- Proto-Oncogene Proteins
- Wnt1 Protein
