Article
Automated dibucaine number measurement with DuPont Dimension ES and AR analyzers.
Clinical chemistry - 1 May 1995
Holownia P, Newman D J, Bruno C, LaGamba P, Gerrits M, Salemink G, Ossani M, Price C P
Abstract excerpt
We report a fully automated method for determining dibucaine number (DN) in a single-run procedure involving Dimension cholinesterase (CHE) Flex pseudo-(P)CHE reagents. The method was developed and optimized with the "open channels" and "kinetic" software facilities of the Dimension-ES instrument, where the DN is calculated automatically by an algorithm from the ratio of the uninhibited and inhibited rates,...
Topics
- Autoanalysis
- Cholinesterase Inhibitors
- Cholinesterases
- Dibucaine
- Humans
- Mutation
- Quality Control
- Sensitivity and Specificity