Article
Preliminary report: genetic variation in the human stromelysin promoter is associated with progression of coronary atherosclerosis.
British heart journal - 1 Mar 1995
Ye S, Watts G F, Mandalia S, Humphries S E, Henney A M
Abstract excerpt
Stromelysin is a member of the family of metalloproteinases that degrade extracellular matrix. In situ hybridisation and histopathological studies suggest that stromelysin activity may be important in the connective tissue remodelling processes associated with atherogenesis and plaque rupture. Si...
Topics
- Base Sequence
- Coronary Angiography
- Coronary Artery Disease
- DNA
- DNA Primers
- Genetic Variation
- Genotype
- Humans
- In Situ Hybridization
- Male
- Matrix Metalloproteinase 3
- Metalloendopeptidases
- Middle Aged
- Molecular Sequence Data
- Polymerase Chain Reaction