Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preliminary report: genetic variation in the human stromelysin promoter is associated with progression of coronary atherosclerosis.

British heart journal - 1 Mar 1995

Ye S, Watts G F, Mandalia S, Humphries S E, Henney A M

Abstract excerpt

Stromelysin is a member of the family of metalloproteinases that degrade extracellular matrix. In situ hybridisation and histopathological studies suggest that stromelysin activity may be important in the connective tissue remodelling processes associated with atherogenesis and plaque rupture. Single strand conformation polymorphism analysis identified a common polymorphism in the stromelysin gene promoter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genotype

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 7727178
DOI: 10.1136/hrt.73.3.209
PMCID: PMC483800

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preliminary report: genetic variation in the human stromelysin promoter is associated with progression of coronary atherosclerosis.PMID 7727178Read ↗

Matrix metalloproteinases: implication in vascular matrix remodelling during atherogenesis.Semantic proximity Read ↗

Stromelysin-1 (MMP-3) gene 5A/6A promoter polymorphism is associated with blood pressure in a community population.Semantic proximity Read ↗

Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression.Semantic proximity Read ↗

Genetic variation in human stromelysin gene promoter and common carotid geometry in healthy male subjects.Semantic proximity Read ↗

Interaction between smoking and the stromelysin-1 (MMP3) gene 5A/6A promoter polymorphism and risk of coronary heart disease in healthy men.Semantic proximity Read ↗

The 5A/6A polymorphism in the promoter of the stromelysin-1 (MMP-3) gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study. Lopid Coronary Angiography Trial.Semantic proximity Read ↗

Stromelysin-1 and interleukin-6 gene promoter polymorphisms are determinants of asymptomatic carotid artery atherosclerosis.Semantic proximity Read ↗

Pharmacogenetic effect of the stromelysin (MMP3) polymorphism on stroke risk in relation to antihypertensive treatment: the genetics of hypertension associated treatment study.Semantic proximity Read ↗

Effect of the stromelysin-1 promoter on efficacy of pravastatin in coronary atherosclerosis and restenosis.Semantic proximity Read ↗

Stromelysin promoter 5A/6A polymorphism is associated with acute myocardial infarction.Semantic proximity Read ↗

Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease.Semantic proximity Read ↗

Haplotype analysis of the stromelysin-1 (MMP3) and gelatinase B (MMP9) genes in relation to coronary heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.