Article
[Genetics of the limb pattern formation in mouse].
Kaibogaku zasshi. Journal of anatomy - 1 Dec 1998
Masuya H
Abstract excerpt
Genetics studies using mouse mutants have revealed key functions of several genes in limb development. In this review, I summarized approaches of forward genetics to elucidate genetic control of mouse limb development based on mouse limb mutants. In mouse, there are many mutants that exhibit malformation in distal elements (autopod) of limb, i.e. polydactyly and ectrodactyly. Some of them are reported as failure...
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