Article
Unique DNA repair property of an ultraviolet-sensitive (radC) mutant of Dictyostelium discoideum.
Photochemistry and photobiology - 1 Mar 1995
Okaichi K, Mori T, Ihara M, Ohnishi T
Abstract excerpt
Dictyostelium discoideum is an organism that shows higher UV resistance than other organisms, such as Escherichia coli and human cultured cells. We examined the removal of cyclobutane pyrimidine dimers (CPD) and 6-4 photoproducts from DNA in the radC mutant and the wild-type strain using an enzyme-linked immunosorbent assay with monoclonal antibodies. Wild-type cells excised more than 90% of both CPD and 6-4...
Topics
- Animals
- Bacterial Proteins
- DNA Repair
- DNA-Binding Proteins
- Dictyostelium
- Escherichia coli Proteins
- Mutation
- Pyrimidine Dimers
- Ultraviolet Rays
