In vivo metabolic effects of insulin-like growth factor-I not mediated through the insulin receptor.

doi:10.1210/jcem.80.4.7714106

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Article

In vivo metabolic effects of insulin-like growth factor-I not mediated through the insulin receptor.

The Journal of clinical endocrinology and metabolism - 1 Apr 1995

Dozio N, Scavini M, Beretta A, Sartori S, Meschi F, Sarugeri E, Pozza G

Abstract excerpt

Patients with mutations affecting insulin receptor function may maintain some degree of metabolic control. The hypothesis has been put forth that in these patients, fuels may be metabolized through pathways (i.e. receptor activation) that become relevant in such abnormal conditions. The aim of ou...

Topics

Adult
Blood
Female
Homozygote
Humans
Hyperglycemia
Hyperinsulinism
Insulin Resistance
Insulin-Like Growth Factor I
Mutation
Receptor, Insulin

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