Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vivo metabolic effects of insulin-like growth factor-I not mediated through the insulin receptor.

The Journal of clinical endocrinology and metabolism - 1 Apr 1995

Dozio N, Scavini M, Beretta A, Sartori S, Meschi F, Sarugeri E, Pozza G

Abstract excerpt

Patients with mutations affecting insulin receptor function may maintain some degree of metabolic control. The hypothesis has been put forth that in these patients, fuels may be metabolized through pathways (i.e. receptor activation) that become relevant in such abnormal conditions. The aim of our study was to evaluate the metabolic effects of insulin-like growth factor-I (IGF-I) in a 19-yr-old patient with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood
Share to Homozygote
Share to Hyperglycemia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hyperinsulinism

Share to Insulin-Like Growth Factor I

Share to Insulin Resistance

Share to Mutation

Share to Receptor, Insulin

Source

Identifiers

PMID: 7714106
DOI: 10.1210/jcem.80.4.7714106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vivo metabolic effects of insulin-like growth factor-I not mediated through the insulin receptor.PMID 7714106Read ↗

Effect of Insulin Deprivation on Muscle Mitochondrial ATP Production and Gene Transcript Levels in Type 1 Diabetic SubjectsSemantic proximity Read ↗

Are the metabolic effects of GH and IGF-I separable?Semantic proximity Read ↗

Mitochondrial diabetes is associated with insulin resistance in subcutaneous adipose tissue but not with increased liver fat content.Semantic proximity Read ↗

Partial rescue of in vivo insulin signalling in skeletal muscle by impaired insulin clearance in heterozygous carriers of a mutation in the insulin receptor gene.Semantic proximity Read ↗

Insulin acutely activates metabolism of primary human monocytes and promotes a proinflammatory phenotype.Semantic proximity Read ↗

Expression of a dominant-negative mutant human insulin receptor in the muscle of transgenic mice.Semantic proximity Read ↗

Insulin and GH Signaling in Human Skeletal Muscle In Vivo following Exogenous GH Exposure: Impact of an Oral Glucose LoadSemantic proximity Read ↗

The role of receptor kinase in insulin action and the effects of insulin on human hepatoma cells.Semantic proximity Read ↗

A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes.Semantic proximity Read ↗

Characterisation of insulin-resistant phenotype of cultured rat primary adipose cells.Semantic proximity Read ↗

Endogenous substrates of the insulin receptor: studies with cells expressing wild-type and mutant receptors.Semantic proximity Read ↗

Biologic activities of naturally occurring human insulin receptor mutations. Evidence that metabolic effects of insulin can be mediated by a kinase-deficient insulin receptor mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.