Article
Studies of hepatic warm ischemia in the obese Zucker rat.
Transplantation - 15 Apr 1995
Koneru B, Reddy M C, dela Torre A N, Patel D, Ippolito T, Ferrante R J
Abstract excerpt
The effects of warm ischemia were investigated in obese Zucker rats with severe hepatic steatosis in order to develop a nontransplant fatty liver ischemia model. Obese (Ob) and lean (Ln) Zucker rats were subjected to in vivo partial hepatic warm ischemia of 45 or 90 min. Injury was assessed by serum alanine aminotransferase, animal survival, and liver histology. Liver lipids were quantified in control animals....
Topics
- Alanine Transaminase
- Animals
- Hot Temperature
- Ischemia
- Leukocyte Count
- Liver
- Malondialdehyde
- Mutation
- Neutrophils
- Obesity
- Rats
- Rats, Zucker